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yirB [2018-07-31 11:32:57]
anti-adaptor protein, inhibits [protein|87124945A1CBF7990856FBEB9EAD25096DAC0868|YjbH]
function
control of proteolysis
product
anti-adaptor protein
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.7|Proteolysis] → [category|SW 3.3.7.4|Additional proteins involved in proteolysis]Gene
Coordinates
3,387,781 → 3,387,945
The protein
Catalyzed reaction/ biological activity
prevention of the [protein|87124945A1CBF7990856FBEB9EAD25096DAC0868|YjbH]-[protein|2C6386E9A63F410558D168798D077DF91590F454|Spx] interaction [Pubmed|21378193]Expression and Regulation
Operons
genes
[gene|5EC57A51EF2DC48070615653B7A3C1007CFEE01D|yirB]
description
[pubmed|30001325]
regulatory mechanism
[protein|1D6C340264B8A75727E202AD2E37053091C94013|YuxN]: repression, [pubmed|30001325], in [regulon|1D6C340264B8A75727E202AD2E37053091C94013|YuxN regulon][protein|A40CD2C23A19860342F440284302EFFDAC09E88A|CssR]: activation, CssR-P acts as anti-repressor [pubmed|30001325], in [regulon|A40CD2C23A19860342F440284302EFFDAC09E88A|CssR regulon]regulation
induced by vancomycin ([protein|A40CD2C23A19860342F440284302EFFDAC09E88A|CssR]-P) [pubmed|30001325]induced by cell wall stress ([protein|A40CD2C23A19860342F440284302EFFDAC09E88A|CssR]) [pubmed|30001325]view in new tabBiological materials
Mutant
BKE33029 (Δ[gene|5EC57A51EF2DC48070615653B7A3C1007CFEE01D|yirB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE33029 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCTAGATTCACCCTTTC, downstream forward: _UP4_TAAAAAAATAGACTGCAAAABKK33029 (Δ[gene|5EC57A51EF2DC48070615653B7A3C1007CFEE01D|yirB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK33029 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCTAGATTCACCCTTTC, downstream forward: _UP4_TAAAAAAATAGACTGCAAAAReferences
